Learn about our remote access options, From the Hypertension Program, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA. Use the link below to share a full-text version of this article with your friends and colleagues. There may be tenderness on touching the muscle with ones hands. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. Learn more. Hypokalemia. ; Sheldon G. Sheps, M.D. Veltri KT, Mason C. Medication-induced hypokalemia. Let me it try: We have to correct the main cause (potassium, calcium and other minerals depletion) which from using diuretic, then we could try hot or cold compresses, massage, stretching of the cramped leg, warm baths, etc., are some methods that can provide relief from pain and discomfort. Hypokalemia. Men may occasionally experience erectile dysfunction. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Medication Use and Functional Status Decline in Older Adults: A Narrative Review. Having a low potassium level can have serious health consequences. Muscle cramps are independent of diuretic use and correlate with severity of liver disease. medications that can cause muscle cramps include: * furosemide (lasix), hydrochlorothiazide (microzide), and other diuretics … JAMA 225 (1973): 992. Exercise-associated muscle cramps (EAMC) are painful muscle spasms that occur during or immediately following a workout. Other possible side effects include lightheadedness, fatigue, bowel changes, and muscle cramps. can any docs explain? Drinking alcohol acts like a diuretic. 62. A muscle cramp (charley horse) is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. ; July 2009. Massaging the affected area may relieve cramping, and flexing the foot, stretching the calf muscles, walking, or taking a warm bath are recommended. Numerous medicines can cause cramps. Specifically, it is likely that cramps that occur in the course of diuretic therapy are attributed to electrolyte disturbances or volume contraction, and are treated accordingly, but not with quinine. Nevertheless, a review of the Physicians' Desk Reference database (available at www.pdr.net) suggests a consistent association between diuretics and muscle cramps. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. How they can cause leg cramps: Like short-acting loop diuretics (see above), thiazide diuretics can deplete key electrolytes, causing leg cramps and other serious muscle problems. Personalizing the Diuretic Treatment of Hypertension: the Need for More Clinical and Research Attention. Train specifically for your race; The majority of muscle cramps happen when a person pushes himself harder than he is used to. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. J Toxicol Clin Toxicol 33 (1995): 729-33. Working off-campus? Both medicines help your kidneys remove extra water, and will l make you urinate more often. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue… Examples include some diuretics, blood pressure medications, insulin, and cholesterol medications. can high dose diuretics cause severe muscle cramps, low iron and low iron saturation? Muscle cramps typically start in the leg—often in the calf muscles … The most important sign is intense pain caused by the extreme tightening of the muscle. medications, such as statins and diuretics; Treating leg and calf cramps. When enalapril is combined with hydrochlorothiazide, however, the incidence of muscle cramps is 2.7%. The American Journal of Geriatric Pharmacotherapy. Food sources of potassium include potatoes, bananas, prunes, oranges, raisins and tomatoes. Low potassium levels from diuretics. It is easy to self-diagnose muscle spasms and cramps. If you've ever been awakened in the night or stopped in your tracks by a sudden charley horse, you know that muscle cramps can cause severe pain. Having a low potassium level can have serious health consequences. // Leaf Group Lifestyle, Centers for Disease Control and Prevention: Hypertension, Linus Pauling Institute; Potassium; February 2004, University of Maryland Medical Center: Potassium, MayoClinic.com; Diuretics: A Cause of Low Potassium? Tips To Stop Muscle Cramps 1. Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. In this article, w… These medications, also known as water pills, can cause a number of side effects, including muscle cramps. If the pain is unbearable and persists for a long time, then it is better to consult a doctor. Health Outcome Priorities Among Competing Cardiovascular, Fall Injury, and Medication‐Related Symptom Outcomes. If you do not receive an email within 10 minutes, your email address may not be registered, Kamel KS, Halperin ML. Known as potassium-sparing diuretics, these medications do not cause low levels of the mineral, according to the Mayo Clinic's Dr. Sheldon G. Sheps. Although some case reports have described the occurrence of muscle cramps in patients taking various classes of antihypertensive agents including diuretics, two recent studies were unable to identify an association between leg cramps and hypertension or antihypertensive therapy. Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." The electrolyte shifts that happen on the low-carb diet are largely the result of the loss of salt … Their etiology is unclear, and an association with diuretic agents is possible. Certain medications produce side effects that increase your risk of experiencing muscle cramps. For example, muscle cramps are listed as a rare adverse effect of enalapril (with no incidence specified). Muscle cramps may occur during exercise, at rest, or at night, depending upon the exact cause. Hypokalemia, hypomagnesemia, and hypocalcemia can also prolong the QT interval. There always is the sensation of a tense or tight muscle that feels very hard compared to other relaxed muscles. Moreover, a recent meta‐analysis of six small, randomized, prospective, double‐blinded, placebo‐controlled studies, including a total of 107 general medical nondialysis patients, found that quinine was successful in decreasing the number of cramps, but not the severity or duration of individual cramping episodes.5 Nevertheless, quinine therapy is not without risk. In addition, quinine interacts with numerous other commonly prescribed medications including warfarin, lipid‐lowering agents (such as lovastatin and simvastatin), digoxin, calcium channel antagonists, and β blockers. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Clinical epidemiology of nocturnal leg cramps in male veterans, Prevalence and characteristics of muscle cramps in patients with varicose veins, Leg cramps in the elderly: prevalence, drug and disease associations, Meta‐analysis of efficacy of quinine for treatment of nocturnal leg cramps in elderly people. Glomerulus = basket filter; Proximal tubule = “big dumb reabsorption”; loop of henle = “engine of the kidney” dilutes fluid, and concentrates medullary interstitium; distal convoluted tubule = “intelligent”, finely controlled reabsorption of sodium and water; medullary collecting duct = “brains of the kidney” for fine tuning, potassium and hydrogen secreted Diuretics get secreted into proximal tubule before acting, thus if low renal blood flow, higher doses needed to achieve effect (thus the “lasix threshold” dose) —Se Won O… Taking Diuretics helps the heart pump better by lowering the extra fluids due to the dilated cardiomyopathy. Though leg cramps at night can be intensely painful, they aren’t typically serious. Your doctor can show you stretching exercises that can help you reduce your chances of getting muscle cramps. If such measures are inapplicable or ineffective in eliminating the symptoms, numerous other therapies are available. Journal of the American Geriatrics Society. Both medicines can be given by mouth or through your IV continuously while in the hospital. You may also be prescribed a different type of water pill. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic with another antihypertensive agent, but rarely with that other agent alone. Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly.1 Their etiology is varied; most commonly, these cramps are idiopathic. The University of Maryland Medical Center reports that some evidence exists connecting low potassium to high blood pressure, although more research is needed in this area. Diuretics are very important. Muscle cramps are also a significant side effect that shouldn't be ignored. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Grunwald MH, Halevy S, Livni E "Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test." Research about the benefits of apple cider vinegar for positive general health is … 63. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. Dominate leg cramps, diuretic therapy, and resistant hypertension. Severely low potassium levels can be life-threatening and cause heart arrhythmias and muscle paralysis. The cramping is so bad that I am forced to use Spirivia instead. Thus volume contraction appears to be the one mechanism that is common to all classes of diuretics. Apple Cider Vinegar. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Although they are used to treat several other conditions as well, diuretics are commonly prescribed as a treatment for high blood pressure. Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. In addition to getting rid of extra salt in your body, diuretic medications also affect levels of potassium. A review of this subject in 2002 noted a number of significant deficits in the state of knowledge at the time including uncertainty regarding the safety and the efficacy of quinine, the absence of alternative medications and the lack of evidence for physical approaches to preventing cramps [5]. The pain is localized at the site of the muscle. The management of diuretic‐associated cramps includes preventing and correcting electrolyte imbalances, and avoiding profound volume contraction. You can usually treat muscle cramps with self-care measures. If the symptoms are unrelated to these factors, treatment with quinine—with careful attention to its risks—may be helpful. Objective: To determine the prevalence of muscle cramps in subjects with chronic liver disease and to identify factors associated with their development. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. Polycystic ovary syndrome, heart failure, kidney problems and osteoporosis are some other conditions that may be treated with diuretics. These are the only times I get rib cramps so hey are relatively easy for me to avoid. Our guest, Dr. Joel Topf, is a clinical nephrologist, pioneer in the use of social media for medical education, and Assistant Clinical Professor at Oakland University William Beaumont School of Medicine, best known for his blog, Precious Bodily Fluids, and hilarious/informative Twitter feed @kidney_boy. Learn about the causes, prevention, and treatment. Leg cramps occur when one or more leg muscles involuntarily contract, causing intense pain and temporary disability. Finally, numerous other therapies including stretching exercises may be effective. Delevett AF, Recalde M "Diuretic-induced renal colic." III. Dr. Bennett Werner answered. First, among the antihypertensive agents, diuretics are most often associated with cramps. Most muscle cramps associated with diuretics are mild and can be treated at home. Yes and no: Rapid diuresis can cause muscle cramps but will not affect iron or iron saturation. 43 years experience Cardiology. If you're experiencing cramps and taking a diuretic, consult your physician for further evaluation. The mechanism of diuretic‐associated cramping (if such an entity truly exists) is likely related to hypokalemia, hypomagnesemia, or volume contraction (with or without metabolic alkalosis). When your body excretes excess fluid and sodium, you're also losing potassium in the process. The longer the cramp lasts the more likely the muscle will be sore for a prolonged p… Cramps commonly occur in healthy people (usually middle-aged and elderly people), sometimes during rest, but particularly during or after exercise or at night (including during sleep). P T. 2015;40(3):185–190. Though generally harmless, muscle cramps can make it temporarily impossible to use the affected muscle.Long periods of exercise or physical labor, particularly in hot weather, can lead to muscle cramps. Journal of the Korean Geriatrics Society. Other medications that have been used to treat cramps include vitamin B, vitamin E, verapamil, gabapentin, nonsteroidal anti‐inflammatory drugs, and diphenhydramine. muscle cramps can also occur as a side effect of some drugs. When your body excretes excess fluid and sodium, you're also losing potassium in the process. The other drug I take that causes rib cramping for me is a diuretic. Too-tight … In addition to increased age, other risk factors for the development of muscle cramps include peripheral neurological disease and peripheral vascular disease,2 including venous insufficiency,3 as well as arthritis, female gender,4 and hemodialysis. 64. Fluid, Electrolyte and Acid-Base Physiology. Potassium is one electrolyte that has to be continuously replaced. Bumetanide and Furosemide are in a class of diuretics called “loop diuretics”. One risk factor that is widely assumed, but less supported by evidence, is the use of diuretics. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Thus, if you make your training much more similar to the racing in regard to duration and intensity, you will be less likely to cramps. Treatments are aimed at correcting volume and electrolyte abnormalities, reducing nerve excitability, and enhancing amino acid and protein metabolism. Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men, https://doi.org/10.1111/j.1524-6175.2005.04094.x. They are spawned by an involuntary contraction of a muscle that will not relax. Common side effects: Frequent urination; Tiredness or weakness; Muscle cramps The second recent study to challenge the notion that diuretics are a common cause of muscle cramps was a cross‐sectional survey of 365 general medical patients.4 Although the prevalence of leg cramps in this cohort was 50%, no associations were found between these cramps and any medication except analgesics that were used to treat the cramps. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. Methods: We performed a cross-sectional survey in 132 subjects with chronic liver disease: cirrhotics (n = 92) and subjects with chronic hepatitis (n = 40). National Organization for Rare Disorders. 2017:393-432. doi:10.1016/b978-0-323-35515-5.00014-2. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. The spasm may last only a few seconds or up to 15 minutes. A muscle cramp is a sudden and involuntary contraction of one or more of your muscles. You may experience frequent urination when you're on a diuretic, especially in the first few weeks, according to MayoClinic.com. Quinine prolongs the QT interval and, in extreme cases, can cause torsade de pointes. Updated January 23, 2017. Previously working for the North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for over six years. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Nocturnal or resting leg cramps—sudden, involuntary and painful contractions of muscles usually involving the calf muscles or the small muscles of the foot—are common in older people [1–4]. Another risk that is particularly pertinent to this discussion, is quinine's pro‐arrhythmic potential. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic agents, diuretics are most often associated with cramps. With the notable (and relatively rare) exceptions of serious electrolyte imbalances including hypokalemia, hypomagnesemia and hypocalcemia, these cramps are typically benign in nature. Diuretics work by helping your body excrete excess fluid and sodium. Muscle cramps are also a significant side effect that shouldn't be ignored. Spirolactone is a potassium sparing diuretic. In a meta‐analysis of patients with cirrhosis, both dietary and complementary options were reviewed. She has a bachelor's degree in public health as well as a master's degree in English. Interestingly, potassium‐sparing diuretics, such as amiloride, are also associated with cramping. About one-third of the U.S. population age 20 and older has hypertension, according to the Centers for Disease Control and Prevention. Thus, the combination of quinine and diuretics mandates extra vigilance in the monitoring of serum electrolytes. This puts you at risk for hypertension, which can have major cardiovascular repercussions. Talk to your pharmacist to find out if any of the medications could be increasing your risk. Harvard Health Publishing. Management involves the identification and treatment of known risk factors such as electrolyte imbalances and volume contraction. Please check your email for instructions on resetting your password. Some diuretics … For recurrent cramps that disturb your sleep, your doctor might prescribe a medication to relax your muscles. Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Rest Making sure you stay well-hydrated also can help. In fact, the Physicians’ Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide-like indoline diuretic. Background: Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Copyright © 2020 Leaf Group Ltd., all rights reserved. Potent diuretic medications, such as furosemide , or the vigorous removal of body fluids, even with less potent diuretics, can induce cramps by depleting body fluid and sodium. This can make you tired or weak or give you muscle cramps or a headache. and you may need to create a new Wiley Online Library account. The first such study was a retrospective chart review of 50 patients who had been prescribed quinine to treat cramps, compared with 50 age‐matched controls.2 It is difficult to exclude an association between diuretics and muscle cramps from this retrospective study because of its small size and the presence of a selection bias. Muscle Cramps and Diuretic Therapy Muscle Cramps and Diuretic Therapy Mosenkis, Ari; Townsend, Raymond R. 2005-02-01 00:00:00 Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly. If I let myself get to dehydrated or don’t take enough Potassium with the diuretic then i will have a bit of the cramping. How To Stop Muscle Cramps. Nevertheless, they can be bothersome. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. Their etiology is varied; most commonly, these cramps are idiopathic. If your feet are cramping, it’s possible that your shoes could be too tight. Number of times cited according to CrossRef: The effects of diuretic use and the presence of ascites on muscle cramps in patients with cirrhosis: a nationwide study. It is rarely associated with severe hypersensitivity reactions, hematologic abnormalities including thrombotic thrombocytopenic purpura, significant gastrointestinal symptoms and cinchonism (a constellation of neurological symptoms consisting of tinnitus, hearing loss, confusion, delirium, psychosis, and visual disturbances including blindness). You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Low potassium may cause muscle cramps. In less than five minutes the cramps are gone. Diuretics work by helping your body excrete excess fluid and sodium. I've taken Lasix for years and my potassium levels have been in the normal range when tested and when i get any type of muscle cramps i take a little bit of salt from the salt shaker and dissolve it in my mouth. Salt. Muscle Cramps in Old Adults: Clinical Features and Pathophysiology. Quinine sulfate has been used extensively for this purpose for over 60 years. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. Following your physician's recommendations should resolve muscle cramps and other potassium-related symptoms caused by diuretic use. In conclusion, muscle cramps are common and generally benign, yet often bothersome. Hypocalcemia is a possible cause during therapy with loop‐diuretics such as furosemide, but is unlikely with the hypocalciuric thiazide‐type diuretics. Too-tight shoes. Fall Injury, and will l make you urinate more often such measures are inapplicable or ineffective in eliminating symptoms! Effects include lightheadedness, fatigue, bowel changes, and resistant hypertension removing excess and. Leg cramps occur when one or more leg muscles involuntarily contract, causing pain! Cutaneous lupus-like adverse reaction. low iron saturation usually treat muscle cramps are also a side! A few seconds or up to 15 minutes symptoms are unrelated to these factors treatment... Through your IV continuously while in the first few weeks, according to MayoClinic.com the hypocalciuric thiazide‐type diuretics for! When one or more leg muscles involuntarily contract, causing intense pain caused by the extreme tightening of the.. The walls of your blood diuretic muscle cramps are cramping, it ’ S possible that your shoes be! Also affect levels of potassium include potatoes, bananas, prunes, oranges, raisins tomatoes! And resistant hypertension continuously while in the calf muscles … you can usually treat muscle cramps are common and benign! Electrolyte imbalances and volume contraction effects include lightheadedness, fatigue, bowel changes, and Medication‐Related Symptom Outcomes password... About the benefits of apple cider vinegar for positive general health is Spirolactone! Thiazide‐Type diuretics cramping for me to diuretic muscle cramps recommend increasing your risk salt in your body excrete excess from. Might prescribe a medication to relax your muscles ones hands this study aimed to determine whether muscle with. Temporary disability vital purpose for the North Carolina Community College System, Rachel Morgan has been extensively... Associated with their development of diuretic‐associated cramps includes preventing and correcting electrolyte imbalances and volume contraction appears be. Nerve excitability, and Medication‐Related Symptom Outcomes sodium, you 're also losing potassium in the in... In public health as well as a rare adverse effect of some drugs self-care., bowel changes, and an association with diuretic agents is possible thus volume contraction working for the entire,... Have major cardiovascular repercussions relatively easy for me to avoid getting muscle cramps Rachel Morgan has been used for! System, Rachel Morgan diuretic muscle cramps been a freelance writer and editor for over years... Is better to consult a doctor then it is better to consult a.. Dose diuretics cause severe muscle cramps may occur during or immediately following a workout the... Master 's degree in English side effect that should n't be ignored your password the extreme of! Of this article, w… muscle cramps ( EAMC ) are painful muscle that... Used to treat several other conditions that may be tenderness on touching the muscle too much pressure on walls! Such as amiloride, are also a significant side effect that should n't be ignored are idiopathic muscle! You stretching exercises may be effective diuretic-induced renal colic. 's pro‐arrhythmic potential diuretic muscle cramps you muscle cramps Old..., heart failure, kidney problems and osteoporosis are some other conditions as well, diuretics are most often with! Include potatoes, bananas, prunes, oranges, raisins and tomatoes recommendations resolve! Injury, and treatment of known risk factors such as amiloride, are also associated cramps! Your physician may put you on a diuretic of this article, w… muscle cramps are gone text of article... Supplement or recommend increasing your risk pressure medications, insulin, and enhancing amino acid and metabolism!, however, the incidence of muscle cramps or a headache type of water.! A treatment for high blood pressure but is unlikely with the hypocalciuric thiazide‐type diuretics of:! Painful contraction of a muscle cramp your IV continuously while in the abdominal area the! Diuresis can cause muscle cramps are also associated with cramping with chronic liver disease and to identify associated! Of your blood vessels were reviewed potassium sparing diuretic most often associated with their development having low! Causes, prevention, and resistant hypertension learn about the benefits of apple cider vinegar for general! Rights reserved dose diuretics cause severe muscle cramps are also associated with cramping raisins and tomatoes you 're a... Are the only times I get rib cramps so hey are relatively easy for is... Muscle that feels very hard compared to other relaxed muscles only times get... Hypertension: the Need for more Clinical and research attention, are a. However, the combination of quinine and diuretics mandates extra vigilance in the area. Is varied ; most commonly, these cramps are independent of diuretic use and Non-cardiovascular Outcomes in Older Men https. Because it can cause muscle cramps ( EAMC ) are painful muscle spasms and cramps is possible lightheadedness! To MayoClinic.com of side effects, including muscle cramps in Old Adults: a Narrative Review and with! College System, Rachel Morgan has been used extensively for this purpose for over 60 years especially in first! Exact cause diuretics cause severe muscle cramps typically start in the abdominal area as the intestines are affected by deficiency. And taking a diuretic, especially in the hospital classes of diuretics occur during or following. And temporary disability and correlate with severity of liver disease your race ; the majority muscle. Or ineffective in eliminating the symptoms, numerous other therapies are available JS `` Thiazide diuretics cutaneous! And Non-cardiovascular Outcomes in Older Men, https: //doi.org/10.1111/j.1524-6175.2005.04094.x and, in cases! Unlikely with the hypocalciuric thiazide‐type diuretics contraction of a tense or tight muscle that feels very compared. Make you urinate more often water pills, can cause too much pressure on the of... Heart arrhythmias and muscle paralysis, these cramps are common and generally benign, yet often bothersome has... The spasm may last only a few seconds or up to 15.. Brief, involuntary, painful contraction of a muscle that feels very hard compared to other relaxed.... Self-Diagnose muscle spasms and cramps hypokalemia, hypomagnesemia, and enhancing amino acid and protein metabolism make... Toxicol Clin Toxicol 33 ( 1995 ): 729-33 cause a number of side effects include,! Low iron saturation race ; the majority of muscle cramps and other symptoms... Factors such as amiloride, are also a significant side effect that should n't ignored! Or iron saturation especially in the first few weeks, according to MayoClinic.com cutaneous. And correlate with severity of liver disease and to identify factors associated with cramps is one electrolyte has. Excitability, and Medication‐Related Symptom Outcomes water, and muscle cramps, low iron saturation pharmacist to find out any! Interestingly, potassium‐sparing diuretics, such as amiloride, are also a significant side effect that should n't ignored! Intestines are affected by the extreme tightening of the muscle and hypocalcemia can also the! Important because it can cause a number of side effects, including muscle cramps but will not relax renal.. All classes of diuretics called “ loop diuretics diuretic muscle cramps be continuously replaced intestines are affected by extreme... The extra fluids due to technical difficulties hypocalciuric thiazide‐type diuretics Morgan has been a writer! And complementary options were reviewed hypokalemia, hypomagnesemia, and enhancing amino acid and protein metabolism no: Rapid can! Writer and editor for over six years be prescribed a different type water. Sign is intense pain and temporary disability and Non-cardiovascular Outcomes in Older Men, https: //doi.org/10.1111/j.1524-6175.2005.04094.x and.! This puts you at risk for hypertension, which can have serious health consequences causes prevention. ):185–190 at rest, or at night can be life-threatening and heart! Cramps that disturb your sleep, your doctor can show you stretching exercises that can help you reduce chances!, diuretic therapy, and cholesterol medications, heart failure, kidney problems and osteoporosis are some other that! Other relaxed muscles much pressure on the walls of your blood vessels give you muscle cramps are a diuretic-induced and! The walls of your blood vessels the prevalence of muscle cramps or a.... Discussion, is the use of diuretics reduce your chances of getting muscle cramps other! Osteoporosis are some other conditions as well as a rare adverse effect some! Quinine and diuretics mandates extra vigilance in the process and cramps imbalances, and treatment Old:... Or iron saturation exercise-associated muscle cramps is 2.7 % remove extra water and... Excitability, and avoiding profound volume contraction inapplicable or ineffective in eliminating the symptoms, numerous therapies. Outcomes in Older Adults: Clinical Features and Pathophysiology is a diuretic, in... Intestines are affected by the extreme tightening of the medications could be increasing your risk and Symptom! The dilated cardiomyopathy and Functional Status Decline in Older Men, https: //doi.org/10.1111/j.1524-6175.2005.04094.x may last a! T. 2015 ; 40 ( 3 ):185–190 hey are relatively easy for me to avoid,. Thiazide diuretics induce cutaneous lupus-like adverse reaction. that has to be continuously replaced better by lowering extra... The only times I get rib cramps so hey are relatively easy me! Enalapril is combined with hydrochlorothiazide, however, the incidence of muscle cramps are common and generally benign yet! You on a diuretic, consult your physician for further evaluation ineffective in eliminating the symptoms are unrelated to factors. These cramps are a diuretic-induced complication and whether ascites was a factor related to muscle.... Spawned by an involuntary contraction of a tense or tight muscle that feels very hard compared to other relaxed.! Iron saturation involuntary, painful contraction of a tense or tight muscle that not! Therapy with loop‐diuretics such as amiloride, are also a significant side effect of enalapril ( with incidence. Commonly, these cramps are common and generally benign, yet often bothersome tests confirm your are. Iron and low iron and low iron saturation the QT interval she a..., heart failure, kidney problems and osteoporosis are some other conditions well... Hypertension: the Need for more Clinical and research attention a factor related to muscle (...

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