8 (2015) 5103–5111. Chen, F.-M. Qiu, X.-M. Zhong, C. Hong, Z. Huang, J. Integr. medical disclaimer The peeled roots of white peony (Paeonia lactiflora) are one of the most common herbs used in Traditional Chinese Medicine, where some of its uses included supporting sleep, emotional stability, mental focus, and immunity. Please enable it to take advantage of the complete set of features! NCI CPTC Antibody Characterization Program. Tools for Trauma: An Interview with Dr. Gabor Maté, Harness the Power of Your Brain-Body Connection: An Interview with Amy Cuddy, Upgrade Your Life: An Interview with Kash Khan. root extract enhances the expression of skin barrier genes via NLM [], [] Top In lung and colon cancer-bearing mice, RP significantly restored food intake and muscle mass, along with muscle function measured by grip strength and treadmill running time. 5938 Priestly Dr., Suite 200 Ther. Luo, A. Li, X. Yang, X. Xiao, R. Hu, T.-W. Wang, X.-Y. 5 (2013) 1113–1116. LLC [13] C.-R. Chen, Y. (http://www.theplantlist.org), a member of the peony family (Paeoniaceae). The ethanol extract of the paeonia root as well as its major active components including gallic acid and methyl gallate were evaluated for their protective effects against free radical generation and lipid peroxidation. Cheng, B.-Z. Res. Wang, Q.-Q. Please read the full Cancer cachexia is a catabolic syndrome driven by inflammation and characterised by a loss of skeletal muscle. Zhao, X.-Y. White peony, technically named Paeonia lactiflora Pall., is a flowering plant native to east Asia. Rep. 13 (2016) 2247–2252. Sun, S. Li, L. Xu, H. Wang, Z. Ma, Q. Fu, R. Qu, S. Ma, Physiol. J Ethnopharmacol. Behav. 41 (2016) 2923–2936. Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 Receptors. Cancer; Gene expression; Inflammation; Signal transduction; Transcriptomics. Lett. [12] D. Yin, Y.-Y. before taking any of the products offered on this site. [Epub ahead of print] Penta-O-galloyl-β-D-glucose from Paeonia lactiflora Pall. 33 (2018) 1175–1185. Ther. Carlsbad, CA 92008, Copyright [1] X. Zhang, Y. Zhai, J. Yuan, Y. Hu, Sci. Paeonia lactiflora was known as the white peony (P. albiflora) when first introduced into Europe. [3] F. Qiu, X. Zhong, Q. Mao, Z. Huang, Exp. [16] H.-Q. Shen, H.-F. Wang, Y. Zhang, C.-G. Shi, S.-C. Zhang, M.-Y. Med. Med. Copyright © 2019 Elsevier B.V. All rights reserved. 1. Shi, M.-Y. It grows in many parts of the world, though, including China, Mongolia, and Siberia. 1089 (2006) 162–170. Epub 2020 Oct 16. 191 (2018) 12–20. [15] D.-Z. Aim of the study: He, Psychopharmacology 236 (2019) 2823–2834. Hu, A.-R. Wang, Z.-Y. 13 (2018) 14. [22] L.-G. Zhang, L.-J. eCollection 2020. 174 (2017) 162–169. Skeletal muscle tissues were analysed by RNAseq, real-time quantitative reverse transcription PCR, western blotting, and immunofluorescence microscopy. Dou, D.-J. White Peony Therapeutic Uses The medicinal properties of White Peony have been researched and analyzed in over a hundred scientific papers, including in vitro, animal, and human studies. Ethanol extract of the peony root(Paeonia Lactiflora Pall, Paeoniaceae)and its ingredients- gallic acid and methyl gallate showed protective effects against free radical generation, i.e. Exp. Li, B. Liu, Neurol. EU/UK Privacy Policy [25] J. Liu, D.-Z. Res. Glycerin (and) Aqua (and) Paeonia Lactiflora Root Extract. 18 (2019) 43–49. 2020 Alibaba.com offers 1,230 paeonia lactiflora root extract products. Molecular mechanisms of cancer cachexia‑induced muscle atrophy (Review). Mao, Z. Huang, Neurosci. Phytessence White Peony by Croda acts as a radiance promotor and brightening agent. Keywords: Med. [8] S.-C. Liu, W.-Y. White peony root extract is standardized to contain not less than 10% paeoniflorin, since this compound is the most researched of white peony root’s unique compounds and is used as the marker compound for standardization. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. [23] X.-Q. (Radix Paeoniae) has been traditionally used to treat various inflammatory diseases in many Asian countries. Hu, W.-M. Qu, J.-F. Chen, N.-N. Cheng, Z.-L. Huang, Psychopharmacology 233 (2016) 281–293. HHS Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. 34 (2014) 184–187. 2020 Jul 1;26:e923199. 21 (2018) 1174–1178. The dried root of Paeonia lactiflora Pall. Behav. Zhang, X.-T. Luo, Y. Ye, X.-Z.  |  Zhu, Brain Res. ALL RIGHTS RESERVED, Privacy Policy Megestrol acetate, which is recommended for the treatment of cachexia in cancer patients, was used as the comparator treatment in this study. The products and information on this website are not intended to diagnose, treat, cure or prevent any disease. J. Integr. COVID-19 is an emerging, rapidly evolving situation. Liu, W.-Y. Neurosci. Yu, Z.-X. If you have more questions, reach out! Xie, X.-Q. ャクヤク(芍薬)はボタン科の多年草。学名 Paeonia J. Pharmacol. 146 (2005) 604–611. Liu, T.-X. Kwan, X. Zhao, Z. Lv, Oncotarget 8 (2017) 8264–8282. Results: Zhang, L. Yang, Y. Li, Z.-C. Xiao, M. Zhang, Z.-Y. We consider the amount of paeoniflorin in a white peony root extract to be the critical factor when determining the dose of an extract to use. Paeonia lactiflora Pall. 10 (2019) 268. Zhang, R.-X. Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . [10] Z.-K. Qiu, J.-L. Atomy Absolute Shampoo Breylee Hyaluronic Acid Face Cream Indy Beauty Antioxidant Hydrating Facial Mist Shangpree Berry Ginseng Eye Mask Madara Micellar Water Sympli Beautiful Rejuvenating Night Cream Madara Micellar Water Satsuma Beauty Collagen Synthesis Face … NEUROHACKER COLLECTIVE, Ethnopharmacological relevance: View abstract. This hair-restoring agent comprises minoxidil, a plant extract of soybeans or Pueraria lobata Ohwi root, and an extract of at least one plant extract selected from the group consisting of Syzygium aromaticum, Paeonia lactiflora , , J. Clin. [26] X.-S. Gu, F. Wang, C.-Y. Zhu, Br. This site needs JavaScript to work properly. 40 (2015) 1583–1592. A wide variety of paeonia lactiflora options are available to you, such as seed, leaf, and shell. Supports healthy behavioral and physiological responses to stress [2–10], Supports adenosine signaling [12,13,15,16], Supports brain-derived neurotrophic factor (BDNF) [4,8,9,18], Supports brain mitochondrial structure and function [19], Supports hippocampal synaptic density [8,19], Modulates glycogen synthase kinase 3β (GSK3β) activity [20,21], Supports neuroprotective functions [15–17,19–25], Supports brain mitochondrial function [19], Supports the composition of the gut microbiota [2]. Preclinical research has also reported that paeoniflorin supports brain protection and repair processes and molecules (such as BDNF and NGF), counters chronic stress, influences learning, and promotes a balanced mood.*. USA.gov. 356 (2016) 64–73. [14] Y. Li, P. Wu, Y. Ning, X. Yan, T. Zhu, C. Ma, A. Liu, J. Tradit. Jin, L. Xiao, X.-Z. Med. † note offer applies to the first shipment of subscription orders. Luo, X. Zhao, J.-F. Chen, Y. Yanagawa, W.-M. Qu, Z.-L. Huang, J. Pharmacol. Here, we'll answer questions about White Peony Root (Paeonia lactiflora, Bai Shao Yao) extract. Only low-to-moderate amounts of white peony are typically needed when paeoniflorin content is more concentrated. Wang, Z.-Z. This study aimed to assess the effects of an ethanolic extract of Radix Paeoniae (RP) on cancer cachexia and elucidate its mechanism of action. free radical scavenging effect against 1,1-diphenyl-2-picryl hydrazine, and lipid peroxidation. Zhang, Chin. J. Pharmacol. Fan, X.-M. Chai, W.-H. Ye, J.-S. Chen, Metab. [6] J. Li, S. Huang, W. Huang, W. Wang, G. Wen, L. Gao, X. Fu, M. Wang, W. Liang, H.Y. Paeonia lactiflora root extract suppresses cancer cachexia by down-regulating muscular NF-κB signalling and muscle-specific E3 ubiquitin ligases in cancer-bearing mice Affiliations 1 Department of Microbiology, Chung-Ang University College of Medicine, Seoul, 06974, Republic of Korea. doi: 10.12659/MSM.923199. In the skeletal muscle tissue of the cancer-bearing mice, RP suppressed NF-κB signalling and reduced inflammatory cytokines, including TNF-α, IL-6, and IL-1β; it also down-regulated the muscle-specific E3 ubiquitin ligases MuRF1 and MAFbx. Ji, Y. Ye, C.-L. Jiang, X.-Z. NIH Rep. 9 (2019) 18469.  |  [20] X. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. [19] D. Wang, L. Liu, S. Li, C. Wang, Physiol. has long been used to treat inflammatory skin diseases, such as psoriasis.Aim of the study: The skin acts as a barrier and provides protection against various stresses by expressing skin barrier genes during keratinocyte differentiation. The purpose of this study was to evaluate the efficacy of Paeonia lactiflora root extract and … In der Traditionellen Chinesischen Medizin (TCM) hat die Pfingstrose eine bedeutende Rolle mit einer langen Anwendungserfahrung.. Schätzungsweise 40 % der Verschreibungen verwenden sie al About 24% of these are Herbal Extract, 0% are Other Extracts. Please speak with an appropriate healthcare professional when evaluating any wellness related therapy. * These statements have not been evaluated by the Food and Drug Administration. 2020 Feb 27;7:5. doi: 10.3389/fnut.2020.00005. [11] H. Huang, J. Zhao, L. Jiang, Y. Xie, Y. Xia, R. Lv, L. Dong, Int. Assessment report on Paeonia lactiflora Pallas, radix (Paeoniae radix alba) Draft Based on Article 10a of Directive 2001/83/EC as amended (well -established use) Based on Article 16d(1), Article 16f and Article 16h of Directiveuse) [2] J.-B. Trotzdem: Bewertung der Pfingstrose könnte sich ändern Medizinisch ist die Pfingstrose durchaus interessant, auch wenn derzeit eine sichere Bewertung nicht möglich erscheint. [24] X. Gu, Z. Cai, M. Cai, K. Liu, D. Liu, Q. Zhang, J. Tan, Q. Ma, Mol. Secure Shopping with 100% industry Standard SSL. Ther. Yang, Z. Dong, Chin. This refers to the color of the processed root, not the color of the flowers. It is one of the four herbs in a TCM herbal formula called Si Ni San, which is used to support sleep quality and help with mental fatigue. White peony root contains a compound called paeoniflorin [1] that in preclinical research influences adenosine signaling—a molecule involved in the sleep homeostatic drive. [21] H.-R. Zhang, J.-H. Peng, X.-B. Yang W, Huang J, Wu H, Wang Y, Du Z, Ling Y, Wang W, Wu Q, Gao W. Mol Med Rep. 2020 Dec;22(6):4967-4980. doi: 10.3892/mmr.2020.11608. RP restored skeletal muscle function and mass in cancer-bearing mice by down-regulating the muscular NF-κB signalling pathway and muscle-specific E3 ubiquitin ligases. Sun, Y.-J. White Peony | Chinese Peony | Radix Paeoniae Alba | Bai Shao, Supports mood*Support brain function*Supports sleep, The peeled roots of white peony (Paeonia lactiflora) are one of the most common herbs used in Traditional Chinese Medicine, where some of its uses included supporting sleep, emotional stability, mental focus, and immunity. Chen, Y.-B. Conclusion: Basic Med. [17] C.-H. Ko, C.-P. Huang, Y.-W. Lin, C.-L. Hsieh, Iran. [9] L.-B. 99 ($9.50/Fl Oz) Xu, Neurochem. Preparation and standardisation of the P. lactiflora root (Radix Paeoniae) extract The herbal raw material consisted of Radix Paeoniae, the dried root of Paeonia lactiflora Pall. Brain Dis. White peony root extract is Non-GMO and Vegan. A Network Pharmacology Approach to Explore the Potential Mechanisms of Huangqin-Baishao Herb Pair in Treatment of Cancer. [18] Y. Zhang, L.-L. Wang, Y. Wu, N. Wang, S.-M. Wang, B. Zhang, C.-G. Shi, S.-C. Zhang, Exp. However, the skin-depigmenting potential of Paeonia lactiflora root extract and its main ingredient paeoniflorin has been scarcely investigated by topical application. White Peony Extract, aka paeonia lactiflora root extract, with paeoniflorin as the active ingredient for healthy immune function. Pharmacol. Radix Paeoniae is the dried root of Paeonia lactiflora Pall. One of our dosing principles is to determine whether there is a dosing range, in which many of the benefits occur and above which there appears to be diminishing returns (i.e., a threshold), and to provide a dose within this threshold range (see Neurohacker Dosing Principles). Liu, K.-Q. Zhu, Br. Other Concerns Functions About the Chemical Synonyms not reported and skin conditioning Paeonia Albiflora Root Extract is an extract of the roots of the peony, Paeonia albiflora. White peony root belongs to the root of Paeonia lactiflora Pall., a perennial herbal plant of the Ranunculaceae family. Hu, W.-Y. [7] S. Wang, X. Zhao, Z. Qiao, X. Jia, Y. Qi, Biomed. 103 (2018) 248–252. Front Nutr. [4] M.-Z. Material and methods: 12 (2016) 3729–3734. 148 (2006) 314–325. Zhang, C.-J. Sci. [5] F.-M. Qiu, X.-M. Zhong, Q.-Q. (http://www.theplantlist.org), a member of the peony family (Paeoniaceae), and has been traditionally used in many Asian countries including China, Korea, Japan, Taiwan, and Thailand for the treatment of diverse inflammatory diseases such as rheumatoid arthritis, hepatitis, and systemic lupus erythematosus (He and Dai, 2011). A cotton material is soaked in a soaking liquid containing an extract from peony (scientific name: Paeonia lactiflora) having high antimicrobial and deodorizing effects among those derived from plants, and heated at a predetermined temperature (121 C) in a pressurized atmosphere in an autoclave, thus enabling the extract from peony to be firmly attached to the cotton material. The root is prescribed in dried, fried or alcohol processed form clinically. Chin. We are focused on making groundbreaking products for health and well-being through complex systems science. Read what Paeonia Lactiflora Root Extract is doing in your skincare and cosmetic formulas and browse products you can find it in. 2019 Oct 23:112337. doi: 10.1016/j.jep.2019.112337. Mao, J. Yang, Y.-P. Yang, S. Liu, L.-F. Hu, C.-F. Liu, Neurochem. The Latin specific epithet lactiflora means “with milk white flowers”. The information on this site is for educational purposes only and should not be considered medical advice. Paeonia lactiflora – 10% Total Glucosides of Peony (TPG) It is said that the ancient Greek healer Paeos used the roots of the white flowering Ranunculaceae plant to heal the gods injured during the Trojan wars. 23 (2017) 696–702. Our study indicates that RP is a potential candidate for development as a therapeutic agent against cancer cachexia. J. About 52% of these are herbal extract, 1% are tea extract. The anti-cachexic effect and mechanism of RP were examined in mouse models of cancer cachexia established in C57BL/6 mice by subcutaneously injecting Lewis lung carcinoma or MC38 colon carcinoma cells. He, X. Liu, J. Zeng, W. Xiao, Q.-H. Zhao, R. Peng, L.-B. Description: Plant extract obtained from the peony (Paeonia Lactiflora root), a flower associated with well-being and rejuvenation.The active ingredient is peoniflorin. Med. Res. Sun, J.-D. Jiang, Y. Wang, Front. Exp. 541 (2013) 209–213. Clipboard, Search History, and several other advanced features are temporarily unavailable. Peony Root Extract INCI Name: PAEONIA LACTIFLORA ROOT EXTRACT Trade name: Peony Root Extract Botanical name: Paeonia lactiflora pall Application: Cosmetics Packaging: in drums Filling Quantity: 25 kg/bag Terms & Conditions Med Sci Monit. It provides moisture, a comfortable application, and … White Peony Tincture, Organic White Peony Extract (Paeonia Lactiflora) Root, Non-GMO in Cold-Pressed Organic Vegetable Glycerin 2 oz, 670 mg 4.4 out of 5 stars 12 $18.99 $ 18 . Pan, J. Fu, S.-R. Ma, P. Han, L. Cong, Z.-W. Zhang, L.-X. Med. A wide variety of paeonia lactiflora root extract options are available to you, such as type, part, and It was brought to England in the mid-18th century, and is the parent of most modern varieties. Alibaba.com offers 757 paeonia lactiflora products. 41 (2019) 446–455. 2 Formulations containing PAEONIA LACTIFLORA ROOT EXTRACT Skin Care: Tone-Up Water Drop Emulsion by Provital It is a waterdrop emulsion, a water in oil formulation, with a high percentage of water that is delivered on the skin upon application. Med. Pharmacother.  |  Miyano K, Ohshima K, Suzuki N, Furuya S, Yoshida Y, Nonaka M, Higami Y, Yoshizawa K, Fujii H, Uezono Y. 24 % of these are Herbal extract, with paeoniflorin as the active for! Mongolia, and immunofluorescence microscopy lactiflora, Bai Shao Yao ) extract Zhi 1990 10:101-2... On the blood coagulative and fibrinolytic enzymes ] N.-N. Cheng, Z.-L. Huang, J. Pharmacol has been scarcely by. Is for educational purposes only and should not be considered medical advice Xiao, R.,... Against Cancer cachexia is a potential candidate for development as a therapeutic agent against Cancer cachexia a loss skeletal! 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